The immunogen is a synthetic peptide directed towards the middle region of human APEX1
Alternative Synonym:
APE, APX, APE1, APEN, APEX, HAP1, REF1
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5 to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene, all encode the same protein.
WB Suggested Anti-APEX1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 293T cell lysateAPEX1 is supported by BioGPS gene expression data to be expressed in HEK293T
APEX1 antibody - middle region (ARP58028_P050) in Human 293T using Western Blot
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten