CD48 (Pan Leukocyte Marker) Antibody, IgG2c, Clone: [CD48/4787], Mouse, Monoclonal

Artikelnummer: NBT-962-MSM7-P1
Artikelname: CD48 (Pan Leukocyte Marker) Antibody, IgG2c, Clone: [CD48/4787], Mouse, Monoclonal
Artikelnummer: NBT-962-MSM7-P1
Hersteller Artikelnummer: 962-MSM7-P1
Alternativnummer: NBT-962-MSM7-P1-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant fragment (around aa 59-178) of human CD48 protein (exact sequence is proprietary)
Alternative Synonym: B-cell activation marker, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, BLAST1, CD48 antigen (B cell membrane protein), Signaling lymphocytic activation molecule 2 (SLAMF2), SLAM family member 2
Reacts with human CD48, a 45kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.
Klonalität: Monoclonal
Klon-Bezeichnung: [CD48/4787]
Molekulargewicht: 45kDa
Isotyp: IgG2c
NCBI: 962
UniProt: P09326
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-emb
Western blot analysis of Raji cell lysate using CD48 Monospecific Mouse Monoclonal Antibody (CD48/4787).
Formalin-fixed, paraffin-embedded human lymph node stained with CD48 Monospecific Mouse Monoclonal Antibody (CD48/4787).
Formalin-fixed, paraffin-embedded human lymph node stained with CD48 Monospecific Mouse Monoclonal Antibody (CD48/4787).
SDS-PAGE Analysis of Purified CD48 Monospecific Mouse Monoclonal Antibody (CD48/4787). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Monospecific Mouse Monoclonal Antibody to CD48 (CD48/4787). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Western blot analysis of Raji cell lysate using CD48 Monospecific Mouse Monoclonal Antibody (CD48/4787).