DRP1 Antibody / Dynamin-related protein 1 / DNM1L, Rabbit, Polyclonal
Biozol Catalog Number:
NSJ-F53331-0.4ML
Supplier Catalog Number:
F53331-0.4ML
Alternative Catalog Number:
NSJ-F53331-0.4ML
Manufacturer:
NSJ Bioreagents
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, WB
Species Reactivity:
Human, Mouse
Immunogen:
This DRP1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 557-590 amino acids from the C-terminal region of human DRP1/DNM1L.
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. [UniProt]
