CD54 / ICAM-1 Antibody - With BSA and Azide, Clone: [F4-31C2], Mouse, Monoclonal
Catalog Number:
ABT-AH11485-U0020
- Images (0)
| Article Name: | CD54 / ICAM-1 Antibody - With BSA and Azide, Clone: [F4-31C2], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH11485-U0020 |
| Supplier Catalog Number: | AH11485-U0020 |
| Alternative Catalog Number: | ABT-AH11485-U0020-20UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IF |
| Species Reactivity: | Human |
| Alternative Names: | Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, CD54, ICAM1 |
| Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors. |
Product Guarantee and Expert Support
