Bovine, Canine, Equine, Goat, Human, Porcine, Rabbit, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human IL17A
Alternative Names:
IL17, CTLA8, IL-17, CTLA-8, IL-17A
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.