CSTB Antibody - N-terminal region

Catalog Number: ASB-ARP59177_P050
Article Name: CSTB Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP59177_P050
Supplier Catalog Number: ARP59177_P050
Alternative Catalog Number: ASB-ARP59177_P050-25UL,ASB-ARP59177_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Equine, Human, Porcine, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CSTB
Alternative Names: PME, ULD, CST6, EPM1, STFB, CPI-B, EPM1A
CSTB is a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in CSTB gene are responsible for the primary defects in patients with progressive myoclonic epilepsy a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 11kDa
NCBI: 1476
UniProt: P04080
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-CSTB Antibody
Catalog Number: ARP59177_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-CSTB Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human heart
CSTB antibody - N-terminal region (ARP59177_P050) validated by WB using Mice brain lysate at 1:2,000.
CSTB antibody - N-terminal region (ARP59177_P050) in Human heart using Western Blot