Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human COPS6
Alternative Names:
CSN6, MOV34-34KD
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
WB Suggested Anti-COPS6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 721_B cell lysateCOPS6 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
Sample Type: ,1. ABAE cells 2. CHO-IR cells Primary Dilution: ,1:200 Secondary Anitbody: ,HRP conjugated anti-rabbit Image Submitted By: ,Dr. Elah Pick University of Haifa at Oranim ,
COPS6 antibody - middle region (ARP59350_P050) in Human 721_B using Western Blot
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