APS-2-79 hydrochloride is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATPbiotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling[1].
Molecular Weight:
423.89
Purity:
98.42
CAS Number:
[2002381-31-7]
Formula:
C23H22ClN3O3
Target:
MEK
Application Notes:
MCE Product type: Reference compound1
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