Creatine Kinase MM Antibody, IgG2a, Clone: [CKMM/3341], Mouse, Monoclonal
Biozol Catalog Number:
NBT-1158-MSM1-P0
Supplier Catalog Number:
1158-MSM1-P0
Alternative Catalog Number:
NBT-1158-MSM1-P0-20,NBT-1158-MSM1-P0-100
Manufacturer:
NeoBiotechnologies
Host:
Mouse
Category:
Antikörper
Application:
ELISA, WB
Species Reactivity:
Human
Immunogen:
Recombinant full-length CKM protein
Alternative Names:
CKM, CKMM, Creatine kinase M, Creatine kinase M chain, Creatine kinase M type, Creatine kinase M-type, Creatine kinase muscle, Creatine kinase, muscle type, M-CK, MCK, Muscle creatine kinase
T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Application Notes:
ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
Formalin-fixed, paraffin-embedded human skeletal muscle stained with Creatine Kinase MM Mouse Monoclonal Antibody (CKMM/3341).
Formalin-fixed, paraffin-embedded human skeletal muscle stained with Creatine Kinase MM Mouse Monoclonal Antibody (CKMM/3341).
Analysis of Protein Array containing more than 19,000 full-length human proteins using Creatine Kinase MM Mouse Monoclonal Antibody (CKMM/3341) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
SDS-PAGE Analysis of Purified CKMM Mouse Monoclonal Antibody(CKMM/3341). Confirmation of Purity and Integrity of Antibody.
Western blot analysis of human Skeletal muscle lysate using Creatine Kinase MM Mouse Monoclonal Antibody (CKMM/3341).
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