Aldo-keto Reductase Family 1 Member C1 / DD1 Antibody, IgG2b, Clone: [AKR1C1/9318], Mouse, Monoclonal

Catalog Number: NBT-1645-MSM18-P1

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Article Name:	Aldo-keto Reductase Family 1 Member C1 / DD1 Antibody, IgG2b, Clone: [AKR1C1/9318], Mouse, Monoclonal
Biozol Catalog Number:	NBT-1645-MSM18-P1
Supplier Catalog Number:	1645-MSM18-P1
Alternative Catalog Number:	NBT-1645-MSM18-P1-100
Manufacturer:	NeoBiotechnologies
Host:	Mouse
Category:	Antikörper
Application:	IHC, WB
Species Reactivity:	Guinea pig, Hamster, Human, Mouse, Rat
Immunogen:	Recombinant human full-length AKR1C1 protein
Alternative Names:	2-dihydrobenzene-1, 2-diol dehydrogenase, 20 alpha (3 alpha) hydroxysteroid dehydrogenase, 20ALPHAHSD, 2ALPHAHSD, AK1C1, C9, Chlordecone reductase homolog HAKRC, DD1/DD2, DDH1, Dihydrodiol dehydrogenase 1/2, H37, HBAB, Hepatic dihydrodiol dehydrogenase, High affinity hepatic bile acid-binding protein, Indanol dehydrogenase, MBAB, Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase, Type II 3 alpha hydroxysteroid dehydrogenase

DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.

Clonality:	Monoclonal
Clone Designation:	[AKR1C1/9318]
Molecular Weight:	37kDa
Isotype:	IgG2b
NCBI:	1645
UniProt:	Q04828
Form:	200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

	Western Blot Analysis of human HepG2 lysate using AKR1C1 Mouse Monoclonal Antibody (AKR1C1/9318).
	1645-MSM18-P1
	SDS-PAGE Analysis of Purified AKR1C1 Mouse Monoclonal Antibody (AKR1C1/9318). Confirmation of Purity and Integrity of Antibody.
	Western blot analysis of (1) human liver, (2) mouse liver, (3) rat liver, (4) hamster liver, (5) guinea pig liver and (6) HepG2 cell lysates using AKR1C1 Mouse Monoclonal Antibody (AKR1C1/9318).
	Western Blot Analysis of A-549 lysate using AKR1C1 Mouse Monoclonal Antibody (AKR1C1/9318).
	Formalin-fixed, paraffin-embedded human hepatocellular carcinoma (HCC) stained with AKR1C1 Mouse Monoclonal Antibody (AKR1C1/9318). Inset: PBS instead of primary antibody, secondary only negative control.

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