This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1mg/ml.
Formalin-fixed, paraffin-embedded human Plac
Formalin-fixed, paraffin-embedded human Lung SqCC stained with EGFR Mouse Monoclonal Antibody (GFR/1667).
Formalin-fixed, paraffin-embedded human Bladder stained with EGFR Mouse Monoclonal Antibody (GFR/1667).
Formalin-fixed, paraffin-embedded human Placenta stained with EGFR Mouse Monoclonal Antibody (GFR/1667).
SDS-PAGE Analysis Purified EGFR Mouse Monoclonal Antibody (GFR/1667). Confirmation of Integrity and Purity of Antibody.
Western Blot Analysis of A431 cell lysate using EGFR Mouse Monoclonal Antibody (GFR/1667).
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