Phospho-Stat6 (Tyr641) (Clone: G12) rabbit mAb PE conjugate, Clone: [Stat6Y641-G12], Rabbit, Monoclonal
Artikelnummer:
ABI-12-4142
Hersteller Artikelnummer:
12-4142
Alternativnummer:
ABI-12-4142-100TESTS
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FACS
Spezies Reaktivität:
Human, Mouse
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr641 of human phospho Stat6
Konjugation:
PE
Alternative Synonym:
Signal transducer and activator of transcription 6, IL-4 Stat
The transcription factor Stat6 is a member of the signal transducers and activators of transcription (STAT) family of proteins. Stat6 is the only member of this family that is activated by interleukin-4 (IL-4), after which Stat6 is both tyrosine- and serine-phosphorylated by Jak kinases. The consensus Stat6 binding site TTCN4GAA is found in the promoters of many genes regulated by IL-4. In T lymphocytes, Stat6 is required for differentiation into Th2 cells in response to IL-4. Stat6 may play a role in solid tumorigenesis, a large immunohistochemistry study of Stat6 expression in over 2,000 tumor samples confirmed strong nuclear staining.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[Stat6Y641-G12]
Formulierung:
Conjugated
Application Verdünnung:
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells or 5 µL per 100 µL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
