Phospho-MSK1 (Thr581) (Clone: A5) rabbit mAb PE conjugate, Clone: [MSK1T581-A5], Rabbit, Monoclonal
Artikelnummer:
ABI-12-4195
Hersteller Artikelnummer:
12-4195
Alternativnummer:
ABI-12-4195-100TESTS
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FACS
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr581 of human phospho MSK1
Konjugation:
PE
Alternative Synonym:
Ribosomal protein S6 kinase alpha-5, S6K-alpha-5, 90 kDa ribosomal protein S6 kinase 5, Nuclear mitogen- and stress-activated protein kinase 1, RSK-like protein kinase, RSKL, RPS6KA5
MSK1 (mitogen and stress activated protein kinase 1, phospho MSK1) is activated by Erk in response to growth factors and by and p38 in response to cellular stress (1). MSK1 is similar to RSK1 in that it has two kinase domains and a connecting regulatory linker region (2). S364/S381 phosphorylation activates RSK1 (3), which is analogous to residues S360 and S376 of MSK1, which may be important for phospho MSK1 activity.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[MSK1T581-A5]
Formulierung:
Conjugated
Application Verdünnung:
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells or 5 µL per 100 µL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for add
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