This human monoclonal antibody clone ANDV-44 was generated as part of a panel using a B cell hybridoma method from an individual previously infected with ANDV.
Alternative Synonym:
Hantavirus, Orthohantavirus, ANDV
Reactivity Species : Andes virus-Hantavirus-Virus Expression Host : HEK-293 Endotoxin Leve : l 1.0 EU/mg as determined by the LAL method Specificity : Clone ANDV-44 competes for binding to a distinct site on the ANDV surface glycoprotein spike, a tetrameric complex composed of Gn and Gc envelope proteins8. Furthermore, antibody ANDV-44 recognizes antigenic site C1 but does not show reactivity to soluble Gc or Gn proteins and may bind to a target site only present in the quaternary spike structure.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[ANDV-44]
Reinheit:
>=95% monomer by analytical SEC
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