Anti-Human HCG (Clone L521)-Purified No Carrier Protein, Clone: [L521], Monoclonal
Artikelnummer:
ABI-12-8308-500
Hersteller Artikelnummer:
12-8308-500
Alternativnummer:
ABI-12-8308-500-500UG
Hersteller:
Abeomics
Kategorie:
Antikörper
Spezies Reaktivität:
Human
Immunogen:
Purified HCG Beta
Specificity: Mouse Anti-Human Chorionic Gonadotropin (HCG) Beta (Clone L521) recognizes Human Chorionic Gonadotropin (HCG) Beta. Background: Human chorionic gonadotropin (hCG) is a hormone produced by cells surrounding a growing embryo, which eventually forms the placenta after implantation1. Its primary function is the maternal recognition of pregnancy, allowing the corpus luteum to secrete progesterone during the first trimester to enrich the uterine lining and sustain the fetus 1. hCG is naturally produced by the syncytiotrophoblast cells of the placenta 1. It is a glycoprotein dimer consisting of an ? subunit identical to other hormones like LH, FSH, and TSH, and a unique ? subunit 4. The genes for the ? and ? subunits are located on different chromosomes 5. The presence of hCG is detected in pregnancy tests due to its elevated levels in pregnant womens urine and blood 1,3. It can also be used to induce ovulation and testosterone production for fertility treatments 1. Historically, hCG was first isolated from the urine of pregnant women in 1928 by Aschheim and Zondek, leading to the development of early pregnancy tests 2. Elevated hCG levels when not pregnant may indicate certain cancers like choriocarcinoma, as some tumors can produce this hormone 1. However, its role in carcinogenesis is unclear.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[L521]
Reinheit:
Purity: >=90% monomer by analytical SEC and SDS-Page Preparation: Antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
