The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
Klonalität:
Monoclonal
Klon-Bezeichnung:
[DM4]
Reinheit:
Purified from cell culture supernatant by affinity chromatography
Formulierung:
Powder
Target-Kategorie:
BCMA
Antibody Type:
Recombinant Antibody
Application Verdünnung:
FACS 1/100, IP 1/30
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