This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals, this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[DM87]
Reinheit:
Purified from cell culture supernatant by affinity chromatography
Target-Kategorie:
PSCA
Antibody Type:
Recombinant Antibody
Application Verdünnung:
ELISA 1/5000-10000,FACS 1/100
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