The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[DM146]
Reinheit:
Purified from cell culture supernatant by affinity chromatography
Target-Kategorie:
CD155
Antibody Type:
Recombinant Antibody
Application Verdünnung:
ELISA 1/5000-10000,FACS 1/100
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