Interferon alpha-1 (IFNA1) Antibody - With BSA and Azide, Clone: [2.52], Mouse, Monoclonal

Artikelnummer: ABT-AH11499-U0020
Artikelname: Interferon alpha-1 (IFNA1) Antibody - With BSA and Azide, Clone: [2.52], Mouse, Monoclonal
Artikelnummer: ABT-AH11499-U0020
Hersteller Artikelnummer: AH11499-U0020
Alternativnummer: ABT-AH11499-U0020-20UG
Hersteller: Abcepta
Wirt: Mouse
Kategorie: Antikörper
Applikation: FC, IF
Spezies Reaktivität: Human
Alternative Synonym: Interferon alpha-1/13, IFN-alpha-1/13, Interferon alpha-D, LeIF D, IFNA1
This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
Klonalität: Monoclonal
Klon-Bezeichnung: [2.52]
NCBI: 3439
UniProt: P01562
Antibody Type: Monoclonal Antibody