Rag1 Antibody - C-terminal region
Artikelnummer:
ASB-ARP42949_P050
- Bilder (3)
| Artikelname: | Rag1 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP42949_P050 |
| Hersteller Artikelnummer: | ARP42949_P050 |
| Alternativnummer: | ASB-ARP42949_P050-25UL,ASB-ARP42949_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Equine, Mouse, Porcine, Rat |
| Immunogen: | The immunogen is a synthetic peptide corresponding to a region of Mouse |
| Alternative Synonym: | Rag, Rag-1 |
| As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. |



