UBR2 Antibody - C-terminal region

Artikelnummer: ASB-ARP43188_P050
Artikelname: UBR2 Antibody - C-terminal region
Artikelnummer: ASB-ARP43188_P050
Hersteller Artikelnummer: ARP43188_P050
Alternativnummer: ASB-ARP43188_P050-25UL,ASB-ARP43188_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human UBR2
Alternative Synonym: C6orf133, bA49A4.1, dJ242G1.1, dJ392M17.3
Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrates destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrates destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM].
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 200kDa
NCBI: 23304
UniProt: Q8IWV8
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-UBR2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: MCF7 cell lysateThere is BioGPS gene expression data showing that UBR2 is expressed in MCF7
Host: Rabbit
Target Name: UBR2
Sample Type: Human Fetal Brain
Antibody Dilution: 1.0ug/ml
UBR2 antibody - C-terminal region (ARP43188_P050) in Human MCF-7 using Western Blot