RNF19A Antibody - N-terminal region
Artikelnummer:
ASB-ARP43197_P050
- Bilder (3)
| Artikelname: | RNF19A Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP43197_P050 |
| Hersteller Artikelnummer: | ARP43197_P050 |
| Alternativnummer: | ASB-ARP43197_P050-25UL,ASB-ARP43197_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human RNF19A |
| Alternative Synonym: | RNF19 |
| RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinsons disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinsons disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported. |
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WB Suggested Anti-RNF19A Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Human brain |
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Host: Rabbit Target: RNF19A Positive control (+): Human brain (BR) Negative control (-): MCF7 (N10) Antibody concentration: 1ug/ml |
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RNF19A antibody - N-terminal region (ARP43197_P050) in Human Brain using Western Blot |
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