MARCH1 Antibody - N-terminal region
Artikelnummer:
ASB-ARP43239_P050
- Bilder (3)
| Artikelname: | MARCH1 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP43239_P050 |
| Hersteller Artikelnummer: | ARP43239_P050 |
| Alternativnummer: | ASB-ARP43239_P050-25UL,ASB-ARP43239_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH1 |
| Alternative Synonym: | MARCH1, RNF171, MARCH-I |
| MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
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WB Suggested Anti-MARCH1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Human Muscle |
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Surface Plasmon Resonance Kinetic Characterization of Polyclonal Antibody Affinity. Purified polyclonal antibodies were immobilized on a Protein A/G coated Carterra LSA sensor chip (PAGH200M) at concentrations of 5, and 50 ug/mL in duplicate. Antibodies on the surface were exposed to interaction with peptides sequentially via microfluidic controlled flow at 333nM peptide concentration for kinetic characterization of the binders for affinity and specificity, followed by curve fitting using the Kinetics software. Kd determinations for both concentrations were averaged and results and standard deviation are shown. |
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MARCH1 antibody - N-terminal region (ARP43239_P050) in Human Muscle using Western Blot |
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