Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human AMACR
Alternative Synonym:
RM, RACE, CBAS4, P504S, AMACRD
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunohistochemistry with Kidney tissue at an antibody concentration of 5ug/ml using anti-AMACR antibody (ARP60806_P050)
AMACR antibody - C-terminal region (ARP60806_P050) validated by WB using 721_B cell lysate at 1.0ug/ml.AMACR is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
AMACR antibody - C-terminal region (ARP60806_P050) in Human 721_B using Western Blot
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