FLNC Antibody - N-terminal region
Artikelnummer:
ASB-ARP64454_P050
- Bilder (3)
| Artikelname: | FLNC Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP64454_P050 |
| Hersteller Artikelnummer: | ARP64454_P050 |
| Alternativnummer: | ASB-ARP64454_P050-25UL,ASB-ARP64454_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N-terminal region of Human FLNC |
| Alternative Synonym: | ABPA, ABPL, FLN2, MFM5, MPD4, RCM5, CMH26, ABP-280, ABP280A |
| This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. |
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WB Suggested Anti-FLNC Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell |
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Surface Plasmon Resonance Kinetic Characterization of Polyclonal Antibody Affinity. Purified polyclonal antibodies were immobilized on a Protein A/G coated Carterra LSA sensor chip (PAGH200M) at concentrations of 5, and 50 ug/mL in duplicate. Antibodies on the surface were exposed to interaction with peptides sequentially via microfluidic controlled flow at 333nM peptide concentration for kinetic characterization of the binders for affinity and specificity, followed by curve fitting using the Kinetics software. Kd determinations for both concentrations were averaged and results and standard deviation are shown. |
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FLNC Antibody - N-terminal region (ARP64454_P050) in Human HepG2 using Western Blot |
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