CYFIP1 Antibody - C-terminal region

Artikelnummer: ASB-ARP64537_P050
Artikelname: CYFIP1 Antibody - C-terminal region
Artikelnummer: ASB-ARP64537_P050
Hersteller Artikelnummer: ARP64537_P050
Alternativnummer: ASB-ARP64537_P050-25UL,ASB-ARP64537_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYFIP1
Alternative Synonym: SHYC, SRA1, SRA-1, P140SRA-1
CYFIP1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. CYFIP1 promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA By similarity. CYFIP1 regulates formation of membrane ruffles and lamellipodia. CYFIP1 plays a role in axon outgrowth. CYFIP1 binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. CYFIP1 may act as an invasion suppressor in cancers.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 145kDa
NCBI: 23191
UniProt: Q7L576
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-CYFIP1 Antibody
Titration: 1.0 ug/ml
Positive Control: COLO205 Whole Cell
Host: Rabbit
Target Name: CYFIP1
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 3ug/ml
CYFIP1 Antibody - C-terminal region (ARP64537_P050) in Human COLO205 using Western Blot