SORT1 Antibody - C-terminal region

Artikelnummer: ASB-ARP64630_P050
Artikelname: SORT1 Antibody - C-terminal region
Artikelnummer: ASB-ARP64630_P050
Hersteller Artikelnummer: ARP64630_P050
Alternativnummer: ASB-ARP64630_P050-25UL,ASB-ARP64630_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Alternative Synonym: NT3, Gp95, NTR3, LDLCQ6
This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes, however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p, the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 84kDa
NCBI: 6272
UniProt: Q99523
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-SORT1 Antibody
Catalog Number: ARP64630_P050
Formalin Fixed Paraffin Embedded Tissue: Human Heart Tissue
Observed Staining: Cytoplasm and plasma membrane in cardiomyocytes
Primary Antibody Concentration: N/A
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-SORT1 Antibody
Titration: 1.0 ug/ml
Positive Control: Hela Whole Cell
SORT1 antibody - C-terminal region (ARP64630_P050) in Hela using Western Blot