BCL6 Antibody - C-terminal region
Artikelnummer:
ASB-OAAB06867
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| Artikelname: | BCL6 Antibody - C-terminal region |
| Artikelnummer: | ASB-OAAB06867 |
| Hersteller Artikelnummer: | OAAB06867 |
| Alternativnummer: | ASB-OAAB06867-400UL |
| Hersteller: | Aviva |
| Wirt: | Mouse |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | This BCL6 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 676-704 amino acids from the C-terminal region of human BCL6. |
| Alternative Synonym: | BCL5, LAZ3, BCL6A, ZNF51, ZBTB27 |
| The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. |
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