DPH2 (AAH16956, 1 a.a. ~ 489 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Alternative Synonym:
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2,diphthamide biosynthesis protein 2 homolog-like 2,diphthamide biosynthesis-like protein 2,diphtheria toxin resistance protein 2,diptheria toxin resistance protein required for diphthamide biosynthesis-like 2,DPH2 homolog,DPH2L2,DPH2-like 2,S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
