RNF2 (NP_009143, 192 a.a. ~ 290 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Alternative Synonym:
BAP1,BAP-1,DING,E3 ubiquitin-protein ligase RING2,HIP2-interacting protein 3,HIPI3,huntingtin-interacting protein 2-interacting protein 3,LUSYAM,protein DinG,RING finger protein 1B,RING finger protein BAP-1,RING1B,RING2,RING-type E3 ubiquitin transferase RING2.
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq
