RHOB Antibody
Artikelnummer:
ASB-OAAN03327
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| Artikelname: | RHOB Antibody |
| Artikelnummer: | ASB-OAAN03327 |
| Hersteller Artikelnummer: | OAAN03327 |
| Alternativnummer: | ASB-OAAN03327-100UL,ASB-OAAN03327-200UL,ASB-OAAN03327-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Synthetic Peptide |
| Alternative Synonym: | ARH6, ARHB, RHOH6, MST081, MSTP081 |
| Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells. |
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