Recombinant Human DnaJ homolog subfamily A member 1 protein (8-106AA)
Konjugation:
Unconjugated
Alternative Synonym:
DJ-2,DjA1,DnaJ (Hsp40) homolog, subfamily A, member 1,dnaJ homolog subfamily A member 1,dnaJ protein homolog 2,hDJ-2,HDJ2,heat shock 40 kDa protein 4,heat shock protein J2,heat shock protein, DNAJ-like 2,HSDJ,HSJ2,HSJ-2,HSPF4,human DnaJ protein 2,NEDD7,neural precursor cell expressed, developmentally down-regulated 7.
Co-chaperone for HSPA8/Hsc70 (PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202).
