JUNB Antibody - N-terminal region
Artikelnummer:
ASB-P100946_T100
- Bilder (3)
| Artikelname: | JUNB Antibody - N-terminal region |
| Artikelnummer: | ASB-P100946_T100 |
| Hersteller Artikelnummer: | P100946_T100 |
| Alternativnummer: | ASB-P100946_T100-25UL,ASB-P100946_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Guinea pig, Human, Mouse, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human JUNB |
| Alternative Synonym: | AP-1 |
| The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. JunB is involved in many types of human carcinoma including T-cell lymphomas, CML,primary cutaneous lymphomas. Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction.JunB is an important regulator of erythroid Differentiation. |
| Klonalität: | Polyclonal |
| Konzentration: | 1.0 mg/ml |
| Molekulargewicht: | 36kDa |
| NCBI: | 3726 |
| Formulierung: | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
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WB Suggested Anti-JUNB Antibody Titration: 1.25ug/ml ELISA Titer: 1:1562500 Positive Control: Transfected 293T |
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Host: Mouse Target Name: JUNB Sample Tissue: Mouse Kidney Antibody Dilution: 1ug/ml |
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JUNB antibody - N-terminal region (P100946_T100) in Human 293T using Western Blot |
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