Hepatitis B Virus Surface Antigen Polyclonal Antibody, Cy5.5 Conjugated, Rabbit
Artikelnummer:
BSS-BS-2327R-CY5.5
Hersteller Artikelnummer:
bs-2327R-Cy5.5
Alternativnummer:
BSS-BS-2327R-CY5.5-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Other, Virus
Konjugation:
Cy5.5
Alternative Synonym:
Hepatitis B, HBSAG_HBVD2, HBSAG_HBVC5, Large envelope protein, Large surface protein, L glycoprotein, Major surface antigen, Large S protein, L-HBsAg, LHB
Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
Klonalität:
Polyclonal
Konzentration:
1ug/ul
Puffer:
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Quelle:
KLH conjugated synthetic peptide derived from HBSAG_HBVD2 sub. ayw pre S1/S2 protein
Target-Kategorie:
Hepatitis B Virus Surface Antigen
Application Verdünnung:
WB(1:300-5000)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
