NSC 122819, inhibit, NSC122819, NSC-122819, Inhibitor, Topoisomerase, Topo II, Teniposide, VM26, VM-26, VM 26
Teniposide (VM-26) is a podophyllotoxin-derived chemotherapeutic agent that acts as a topoisomerase II inhibitor, stabilizing the enzyme-DNA complex to block DNA replication. It is widely used in cancer research, demonstrating activity in both in vitro cytotoxicity assays and in vivo models of leukemia and solid tumors.