Inhibitor, NucleosideAntimetabolite, Nucleoside Antimetabolite/Analog, Nucleoside Antimetabolite, NSC127716, NSC-127716, inhibit, NSC 127716, Analog, Apoptosis, 5-Aza-2-deoxycytidine, 5-Aza-CdR, Dacogen, Decitabine, Deoxycytidine, DNA MTases, DNA Methyltransferase, DNA methyltransferase (DNMT), DNMTs, DNAMethyltransferase
Decitabine is an orally active deoxycytidine analog and DNA methyltransferase inhibitor. It exhibits antitumor and antimetabolic activity by inducing DNA hypomethylation, leading to cell cycle arrest and apoptosis in both in vitro and in vivo cancer research models.
