inotropic, human cardiac, function, inhibit, MYK 491, MYK491, MYK-491, Myosin, Inhibitor, allosteric, acto-myosin, cardiac, Danicamtiv, SAR440181, SAR-440181, SAR 440181, systolic
Danicamtiv (MYK-491) is a selective cardiac myosin activator that functions as an inotropic agent. It enhances systolic performance while maintaining mechanical efficiency, making it a valuable research tool for studying heart failure pathophysiology and cardiac contractility in both cellular and animal models.