PANKi is a potent, reversible inhibitor of pantothenate kinase isoforms, the rate-limiting enzyme in CoA biosynthesis. It exhibits mixed-type inhibition and, at low micromolar concentrations, inhibits cellular CoA production and synergizes with compounds like BSO to induce ferroptosis in cancer cell lines, providing a research tool for studying metabolism and cell death.
Molekulargewicht:
391.49
CAS Nummer:
[902614-04-4]
Formel:
C21H21N5OS
Target-Kategorie:
Others
Cas No. 902614-04-4
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