Keap1-Nrf2-IN-6 is a highly potent and selective small molecule inhibitor that disrupts the Keap1-Nrf2 protein-protein interaction, with an IC50 of 41 nM and a Kd of 68 nM. This inhibitor is a valuable chemical probe for investigating the Nrf2-mediated antioxidant response pathway in both cellular and animal models of oxidative stress and inflammation.
Molekulargewicht:
610.68
Formel:
C30H34N4O8S
Target-Kategorie:
Others,Nrf2
Structure of Keap1-Nrf2-IN-6
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