CLDN6/CLD6 Antibody, Unconjugated, Monoclonal
Artikelnummer:
BYT-ORB1805484
- Bilder (6)
| Artikelname: | CLDN6/CLD6 Antibody, Unconjugated, Monoclonal |
| Artikelnummer: | BYT-ORB1805484 |
| Hersteller Artikelnummer: | orb1805484 |
| Alternativnummer: | BYT-ORB1805484-1,BYT-ORB1805484-100 |
| Hersteller: | Biorbyt |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FA, FACS, In vivo |
| Spezies Reaktivität: | Human |
| Konjugation: | Unconjugated |
| Anti-CLDN6 Reference Antibody is expressed from CHO. The heavy chain type is IgG1, and the light chain type is hukappa. It has a predicted MW of 150kDa. |
| Klonalität: | Monoclonal |
| Konzentration: | Batch dependent |
| Molekulargewicht: | 145.84 kDa |
| UniProt: | P56747 |
| Puffer: | 100 mM Proline/Acetic acid 20mM Arginine pH 5.0 |
| Reinheit: | >95% |
| Target-Kategorie: | CLDN6 / CLD6 |
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Anti-CLDN6 Reference Antibody (DS-9606a) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%. |
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The purity of Anti-CLDN6 Reference Antibody (DS-9606a)is more than 99.37% ,determined by SEC-HPLC. |
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Immobilized human CLDN6 VLP Protein at 2 µg/mL can bind Anti-CLDN6 Reference Antibody (DS-9606a),EC50=0.00407 µg/mL. |
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Human CLDN6 CHO cells were stained with Anti-CLDN6 Reference Antibody (DS-9606a) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC64=3.036 nM. |
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DS-9606a by huCLDN6-HEK293 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 60% at antibody concentration of 1 nM. |
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DS-9606a inhibited the tumor growth of PA-1 on Balb/c nude mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 84.7% at 5 mpk at D46. |
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