Anti-OSMR Reference Antibody is expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hulambda. It has a predicted MW of 145.5 kDa.
Anti-OSMR Reference Antibody (vixarelimab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-OSMR Reference Antibody (vixarelimab)is more than 96.9% ,determined by SEC-HPLC.
Immobilized human OSMR His at 2 µg/mL can bind Anti-OSMR Reference Antibody (vixarelimab),EC50=0.0024µg/mL.
Human OSMR HEK293 cells were stained with Anti-OSMR Reference Antibody (vixarelimab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC261=0.0359 µg/mL.
Anti-OSMR Reference Antibody (vixarelimab) P-STAT3 Assay was evaluated using NHDF. The IC50 was approximately 0.3493 nM.
Anti-OSMR Reference Antibody (vixarelimab),MCP-1 secretion was evaluated using NHDF. The IC50 was approximately 0.0812 nM.
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