GPC3/Glypican-3 Antibody, Unconjugated, Monoclonal
Artikelnummer:
BYT-ORB1806346
- Bilder (6)
| Artikelname: | GPC3/Glypican-3 Antibody, Unconjugated, Monoclonal |
| Artikelnummer: | BYT-ORB1806346 |
| Hersteller Artikelnummer: | orb1806346 |
| Alternativnummer: | BYT-ORB1806346-1,BYT-ORB1806346-100 |
| Hersteller: | Biorbyt |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FA, FACS, In vivo |
| Spezies Reaktivität: | Human |
| Konjugation: | Unconjugated |
| Anti-GPC3 / Glypican-3 Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa. |
| Klonalität: | Monoclonal |
| Konzentration: | Batch dependent |
| Molekulargewicht: | 145.5 kDa |
| UniProt: | P51654 |
| Puffer: | 100 mM Proline/Acetic acid 20mM Arginine pH 5.0 |
| Reinheit: | >95% |
| Target-Kategorie: | GPC3 / Glypican-3 |
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Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%. |
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The purity of Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab)is more than 95% ,determined by SEC-HPLC. |
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Immobilized human GPC3, His tag at 2 µg/mL can bind Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab),EC50=0.008741µg/mL. |
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Human GPC3 CHOS cells were stained with Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC210=2.142 nM. |
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The endocytosis ratio codrituzumab by HuH-7 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 40%at antibody concentration of 1 nM. |
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Anti-GPC3 / Glypican-3 Reference Antibody (Codrituzumab)-induced ADCC activity was evaluated using human GPC3 CHOS Cell. The max Lysis rate was approximately 30%. |
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