FGFR2/CD332 Antibody, Unconjugated, Monoclonal
Artikelnummer:
BYT-ORB1806350
- Bilder (6)
| Artikelname: | FGFR2/CD332 Antibody, Unconjugated, Monoclonal |
| Artikelnummer: | BYT-ORB1806350 |
| Hersteller Artikelnummer: | orb1806350 |
| Alternativnummer: | BYT-ORB1806350-1,BYT-ORB1806350-100 |
| Hersteller: | Biorbyt |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FA, FACS, In vivo |
| Spezies Reaktivität: | Human |
| Konjugation: | Unconjugated |
| Anti-FGFR2 / CD332 Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.24 kDa. |
| Klonalität: | Monoclonal |
| Konzentration: | Batch dependent |
| Molekulargewicht: | 144 kDa |
| UniProt: | P21802 |
| Puffer: | 100 mM Proline/Acetic acid 20mM Arginine pH 5.0 |
| Reinheit: | >95% |
| Target-Kategorie: | FGFR2 / CD332 |
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Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%. |
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The purity of Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab)is more than 100% ,determined by SEC-HPLC. |
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SNU-16 cells were stained with Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC763=0.5368 µg/mL. |
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Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab) induced ADCC activity was evaluated using Human FGFR2 HEK293 Reporter Cell.The max induction fold was approximately 25. |
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Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab) -ADCC luciferase Assay on KATOIII cells. The maximum suppression factor is approximately 14. |
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Bemarituzumab inhibited the tumor growth of SNU-16 on Balb/c nude mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 29.7% at 2 mpk at D62. |
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