CD20 Antibody, Unconjugated, Monoclonal

Artikelnummer: BYT-ORB1806379
Artikelname: CD20 Antibody, Unconjugated, Monoclonal
Artikelnummer: BYT-ORB1806379
Hersteller Artikelnummer: orb1806379
Alternativnummer: BYT-ORB1806379-1,BYT-ORB1806379-100
Hersteller: Biorbyt
Kategorie: Antikörper
Applikation: ELISA, FA, FACS, In vivo
Spezies Reaktivität: Human, Monkey
Konjugation: Unconjugated
Anti-CD20 Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 146.32 kDa.
Klonalität: Monoclonal
Konzentration: Batch dependent
Molekulargewicht: 145.2 kDa
UniProt: P11836
Puffer: 100 mM Proline/Acetic acid 20mM Arginine pH 5.0
Reinheit: >95%
Target-Kategorie: CD20
Anti-CD20 Reference Antibody (rituximab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-CD20 Reference Antibody (rituximab)is more than 98.97% ,determined by SEC-HPLC.
Immobilized human EGFR His at 2 µg/mL can bind Anti-CD20 Reference Antibody (rituximab),EC50=0.01573/0.01258µg/mL.
Raji cells were stained with Anti-CD20 Reference Antibody (rituximab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC87=1.334 µg/mL.
Anti-CD20 Reference Antibody (rituximab)-induced CDC activity was evaluated using Raji Cell. The max Lysis rate was approximately 74%.
Anti-CD20 Reference Antibody (rituximab)-induced ADCC activity was evaluated using Raji Cell. The max Lysis rate was approximately 35%.