Synthesized peptide derived from RASSF8 . at AA range: 60-140
Alternative Synonym:
RASSF8, C12orf2, Ras association domain-containing protein 8, Carcinoma-associated protein HOJ-1
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12,22)(p11.2,q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],
