Synthesized peptide derived from DNA Pol µ . at AA range: 210-290
Alternative Synonym:
POLM, polmu, DNA-directed DNA/RNA polymerase mu, Pol Mu, Terminal transferase
catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Western Blot analysis of extracts from K562 cells, using DNA Pol µ Polyclonal Antibody. Secondary antibody(catalog:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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