The antiserum was produced against synthesized peptide derived from the Internal region of human FCGR2B/C. AA range:141-190
Alternative Synonym:
FCGR2B, CD32, FCG2, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, CD32, FCGR2C, CD32, FCG2, IGFR2,Low affinity immunoglobulin gamma Fc region receptor II-c, IgG Fc receptor II-c, CDw32, Fc-gamma RII-c, Fc-gamma-RIIc, FcRII-c, CD32
Low affinity immunoglobulin gamma Fc region receptor II-b/Low affinity immunoglobulin gamma Fc region receptor II-c encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
