The antiserum was produced against synthesized peptide derived from human FAF1. AA range:531-580
Alternative Synonym:
FAF1, UBXD12, UBXN3A, CGI-03, FAS-associated factor 1, hFAF1, UBX domain-containing protein 12, UBX domain-containing protein 3A
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008],
