The antiserum was produced against synthesized peptide derived from human SH2D1B. AA range:71-120
Alternative Synonym:
SH2D1B, EAT2, SH2 domain-containing protein 1B, EWS/FLI1-activated transcript 2, EAT-2
By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008],
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using SH2D1B Antibody. The picture on the right is blocked with the synthesized peptide.
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