The antiserum was produced against synthesized peptide derived from human PLA2G4E. AA range:401-450
Alternative Synonym:
PLA2G4E, Cytosolic phospholipase A2 epsilon, cPLA2-epsilon, Phospholipase A2 group IVE
catalytic activity:Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.,domain:The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca(2+).,enzyme regulation:Stimulated by cytosolic Ca(2+).,function:Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PLA2c domain.,subcellular location:Translocates to lysosomal membranes in a calcium-dependent fashion.,
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using PLA2G4E Antibody. The picture on the right is blocked with the synthesized peptide.
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